FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CyPA
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
18kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human PPIA. AA range:51-100
特异性
CyPA Polyclonal Antibody detects endogenous levels of CyPA protein.
基因名称
PPIA
蛋白名称
Peptidyl-prolyl cis-trans isomerase A
别名
PPIA;CYPA;Peptidyl-prolyl cis-trans isomerase A;PPIase A;Cyclophilin A;Cyclosporin A-binding protein;Rotamase A
Organism-1
Human
基因ID-1
5478
SwissProt-1
P62937
Organism-2
Mouse
基因ID-2
268373
SwissProt-2
P17742
Organism-3
Rat
基因ID-3
100360977
SwissProt-3
P10111
背景
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Secreted . Nucleus . Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that includes Rho GTPase signaling, actin remodeling, and myosin II activation. .
