FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SSX
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the C-terminal region of human SSX1/2/3/4/5/6/7/8/9. AA range:139-188
特异性
SSX Polyclonal Antibody detects endogenous levels of SSX protein.
基因名称
SSX1/SSX2/SSX3/SSX4/SSX5/SSX6/SSX7/SSX8/SSX9
蛋白名称
Protein SSX1/Protein SSX2/Protein SSX3/Protein SSX4/Protein SSX5/Protein SSX6/Protein SSX7/Protein SSX8/Protein SSX9
别名
SSX1;Protein SSX1;Cancer/testis antigen 5.1;CT5.1;Synovial sarcoma, X breakpoint 1;SSX2;SSX2A;SSX2B;Protein SSX2;Cancer/testis antigen 5.2;CT5.2;Synovial sarcoma, X breakpoint 2;Tumor antigen HOM-MEL-40;SSX3;Protein SSX3;Cancer/testis antigen 5.3;CT5.3;SSX4;SSX4A;SSX4B;Protein SSX4;Cancer/testis antigen 5.4;CT5.4;SSX5;Protein SSX5;SSX6;Putative protein SSX6;SSX7;Protein SSX7;SSX8;Protein SSX8;SSX9;Protein SSX9
Organism-1
Human
基因ID-1
6756
SwissProt-1
Q16384
背景
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013],
细胞定位
nucleus,
