FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
BNIP-3
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120
特异性
BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.
基因名称
BNIP3
蛋白名称
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
别名
BNIP3;NIP3;BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Organism-1
Human
基因ID-1
664
SwissProt-1
Q12983
Organism-2
Mouse
SwissProt-2
O55003
背景
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
细胞定位
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
