- 产品信息
商品描述
靶点-Target
ET-1
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
IHC: 100-300;WB 1:500-1:2000;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
特异性
ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
基因名称
EDN1
蛋白名称
Endothelin-1
别名
EDN1;Endothelin-1;Preproendothelin-1;PPET1
Organism-1
Human
基因ID-1
1906
SwissProt-1
P05305
Organism-2
Mouse
SwissProt-2
P22387
背景
This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
细胞定位
Secreted.





