Prothrombin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616970
- 产品信息
商品描述
靶点-Target
Prothrombin
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human Prothrombin. AA range 420-470
特异性
Prothrombin Polyclonal Antibody detects endogenous levels of Prothrombin protein.
基因名称
F2
蛋白名称
Prothrombin
别名
F2;Prothrombin;Coagulation factor II
Organism-1
Human
基因ID-1
2147
SwissProt-1
P00734
Organism-2
Mouse
基因ID-2
14061
SwissProt-2
P19221
Organism-3
Rat
SwissProt-3
P18292
背景
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
细胞定位
Secreted, extracellular space.





