Prothrombin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616970

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商品描述
  • 靶点-Target

    Prothrombin

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    70kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the Internal region of human Prothrombin. AA range 420-470

  • 特异性

    Prothrombin Polyclonal Antibody detects endogenous levels of Prothrombin protein.

  • 基因名称

    F2

  • 蛋白名称

    Prothrombin

  • 别名

    F2;Prothrombin;Coagulation factor II

  • Organism-1

    Human

  • 基因ID-1

    2147

  • SwissProt-1

    P00734

  • Organism-2

    Mouse

  • 基因ID-2

    14061

  • SwissProt-2

    P19221

  • Organism-3

    Rat

  • SwissProt-3

    P18292

  • 背景

    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

  • 细胞定位

    Secreted, extracellular space.