- 产品信息
商品描述
靶点-Target
Actin skeletal muscle α
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human α-SMA.
特异性
α-SMA Polyclonal Antibody detects endogenous levels of α-SMA protein.
基因名称
ACTA1/ACTA2/ACTC1
蛋白名称
Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin alpha cardiac muscle 1
别名
ACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein;ACTC1;ACTC;Actin, alpha cardiac muscle 1;Alpha-cardiac actinACTA1;ACTA;Actin, alpha skeletal muscle;Alpha-actin-1;ACTA2;ACTSA;ACTVS;GIG46;Actin, aortic smooth muscle;Alpha-actin-2;Cell growth-inhibiting gene 46 protein;ACTC1;ACTC;Actin, alpha cardiac muscle 1;Alpha-cardiac actin
Organism-1
Human
基因ID-1
59
SwissProt-1
P68133
Organism-2
Mouse
基因ID-2
11459
SwissProt-2
P68134
Organism-3
Rat
基因ID-3
29437
SwissProt-3
P68136
背景
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytoskeleton.





