NF-L Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616944

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商品描述
  • 靶点-Target

    NF-L

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    61kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the C-terminal region of human NF-L.

  • 特异性

    NF-L Polyclonal Antibody detects endogenous levels of NF-L protein.

  • 基因名称

    NEFL

  • 蛋白名称

    Neurofilament light polypeptide

  • 别名

    NEFL;NF68;NFL;Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein

  • Organism-1

    Human

  • 基因ID-1

    4747

  • SwissProt-1

    P07196

  • Organism-2

    Mouse

  • 基因ID-2

    18039

  • SwissProt-2

    P08551

  • Organism-3

    Rat

  • 基因ID-3

    83613

  • SwissProt-3

    P19527

  • 背景

    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],

  • 细胞定位

    Cell projection, axon . Cytoplasm, cytoskeleton .