- 产品信息
商品描述
靶点-Target
NF-L
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
61kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human NF-L.
特异性
NF-L Polyclonal Antibody detects endogenous levels of NF-L protein.
基因名称
NEFL
蛋白名称
Neurofilament light polypeptide
别名
NEFL;NF68;NFL;Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein
Organism-1
Human
基因ID-1
4747
SwissProt-1
P07196
Organism-2
Mouse
基因ID-2
18039
SwissProt-2
P08551
Organism-3
Rat
基因ID-3
83613
SwissProt-3
P19527
背景
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008],
细胞定位
Cell projection, axon . Cytoplasm, cytoskeleton .





