FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NPRL2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human NPRL2.
特异性
NPRL2 Polyclonal Antibody detects endogenous levels of NPRL2 protein.
基因名称
NPRL2
蛋白名称
Nitrogen permease regulator 2-like protein
别名
NPRL2;TUSC4;Nitrogen permease regulator 2-like protein;NPR2-like protein;Gene 21 protein;G21 protein;Tumor suppressor candidate 4
Organism-1
Human
基因ID-1
10641
SwissProt-1
Q8WTW4
Organism-2
Mouse
基因ID-2
56032
SwissProt-2
Q9WUE4
背景
function:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.,similarity:Belongs to the NPR2 family.,subunit:Interacts with PDPK1.,tissue specificity:Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.,
细胞定位
Lysosome membrane . Localization to lysosomes is amino acid-independent. .
