FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SS-56
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human SS-56.
特异性
SS-56 Polyclonal Antibody detects endogenous levels of SS-56 protein.
基因名称
TRIM68
蛋白名称
E3 ubiquitin-protein ligase TRIM68
别名
TRIM68;GC109;RNF137;SS56;E3 ubiquitin-protein ligase TRIM68;RING finger protein 137;SSA protein SS-56;SS-56;Tripartite motif-containing protein 68
Organism-1
Human
基因ID-1
55128
SwissProt-1
Q6AZZ1
Organism-2
Mouse
SwissProt-2
Q8K243
背景
This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
细胞定位
Cytoplasm, perinuclear region. Nucleus. Colocalized with AR in nucleus.
