FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UBE2A/B
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
17kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human UBE2A/B.
特异性
UBE2A/B Polyclonal Antibody detects endogenous levels of UBE2A/B protein.
基因名称
UBE2A/UBE2B
蛋白名称
Ubiquitin-conjugating enzyme E2 A/Ubiquitin-conjugating enzyme E2 B
别名
UBE2A;RAD6A;Ubiquitin-conjugating enzyme E2 A;RAD6 homolog A;HR6A;hHR6A;Ubiquitin carrier protein A;Ubiquitin-protein ligase A;UBE2B;RAD6B;Ubiquitin-conjugating enzyme E2 B;RAD6 homolog B;HR6B;hHR6B;Ubiquitin carrier protein B;Ubiquitin-conjugating enzyme E2-17 kDa;Ubiquitin-protein ligase B
Organism-1
Human
基因ID-1
7320
SwissProt-1
P49459;P63146
Organism-3
Rat
基因ID-3
81816
SwissProt-3
P63149
背景
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
细胞定位
chromatin,nuclear chromatin,XY body,cytoplasm,cytosol,HULC complex,
