- 产品信息
商品描述
靶点-Target
SV2C
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
82kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human SV2C. AA range 330-390
特异性
SV2C Polyclonal Antibody detects endogenous levels of SV2C protein.
基因名称
SV2C
蛋白名称
Synaptic vesicle glycoprotein 2C
别名
SV2C;KIAA1054;Synaptic vesicle glycoprotein 2C
Organism-1
Human
基因ID-1
22987
SwissProt-1
Q496J9
Organism-2
Mouse
基因ID-2
75209
SwissProt-2
Q69ZS6
Organism-3
Rat
基因ID-3
29643
SwissProt-3
Q9Z2I6
背景
function:Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.,PTM:N-glycosylated.,similarity:Belongs to the major facilitator superfamily.,subcellular location:Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.,subunit:Interacts with SYT1 in a calcium-dependent manner.,
细胞定位
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas. .





