FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SLP-76
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from SLP-76 . at AA range: 270-350
特异性
SLP-76 Polyclonal Antibody detects endogenous levels of SLP-76 protein.
基因名称
LCP2
蛋白名称
Lymphocyte cytosolic protein 2
别名
LCP2;Lymphocyte cytosolic protein 2;SH2 domain-containing leukocyte protein of 76 kDa;SLP-76 tyrosine phosphoprotein;SLP76
Organism-1
Human
基因ID-1
3937
SwissProt-1
Q13094
Organism-2
Mouse
基因ID-2
16822
SwissProt-2
Q60787
背景
SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T c
细胞定位
Cytoplasm .
