- 产品信息
商品描述
靶点-Target
SNM1B
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human SNM1B.
特异性
SNM1B Polyclonal Antibody detects endogenous levels of SNM1B protein.
基因名称
DCLRE1B
蛋白名称
5' exonuclease Apollo
别名
DCLRE1B;SNM1B;5' exonuclease Apollo;DNA cross-link repair 1B protein;SNM1 homolog B;SNMIB;hSNM1B
Organism-1
Human
基因ID-1
64858
SwissProt-1
Q9H816
Organism-2
Mouse
SwissProt-2
Q8C7W7
背景
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008],
细胞定位
Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.





