- 产品信息
商品描述
靶点-Target
APLP-1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from APLP-1 . at AA range: 360-440
特异性
APLP-1 Polyclonal Antibody detects endogenous levels of APLP-1 protein.
基因名称
APLP1
蛋白名称
Amyloid-like protein 1
别名
APLP1;Amyloid-like protein 1;APLP;APLP-1
Organism-1
Human
基因ID-1
333
SwissProt-1
P51693
Organism-2
Mouse
基因ID-2
11803
SwissProt-2
Q03157
背景
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Single-pass type I membrane protein.; [C30]: Cytoplasm. C-terminally processed in the Golgi complex.





