- 产品信息
商品描述
靶点-Target
Elmo1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
83kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Elmo1. AA range:22-71
特异性
Elmo1 Polyclonal Antibody detects endogenous levels of Elmo1 protein.
基因名称
ELMO1
蛋白名称
Engulfment and cell motility protein 1
别名
ELMO1;KIAA0281;Engulfment and cell motility protein 1;Protein ced-12 homolog
Organism-1
Human
基因ID-1
9844
SwissProt-1
Q92556
Organism-2
Mouse
基因ID-2
140580
SwissProt-2
Q8BPU7
背景
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
细胞定位
Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.





