Elmo1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616884

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商品描述
  • 靶点-Target

    Elmo1

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    83kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Elmo1. AA range:22-71

  • 特异性

    Elmo1 Polyclonal Antibody detects endogenous levels of Elmo1 protein.

  • 基因名称

    ELMO1

  • 蛋白名称

    Engulfment and cell motility protein 1

  • 别名

    ELMO1;KIAA0281;Engulfment and cell motility protein 1;Protein ced-12 homolog

  • Organism-1

    Human

  • 基因ID-1

    9844

  • SwissProt-1

    Q92556

  • Organism-2

    Mouse

  • 基因ID-2

    140580

  • SwissProt-2

    Q8BPU7

  • 背景

    This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

  • 细胞定位

    Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.