- 产品信息
商品描述
靶点-Target
MCAD
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
46kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MCAD. AA range:134-183
特异性
MCAD Polyclonal Antibody detects endogenous levels of MCAD protein.
基因名称
ACADM
蛋白名称
Medium-chain specific acyl-CoA dehydrogenase mitochondrial
别名
ACADM;Medium-chain specific acyl-CoA dehydrogenase, mitochondrial;MCAD
Organism-1
Human
基因ID-1
34
SwissProt-1
P11310
Organism-2
Mouse
基因ID-2
11364
SwissProt-2
P45952
Organism-3
Rat
基因ID-3
24158
SwissProt-3
P08503
背景
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .





