Ihh Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616877

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商品描述
  • 靶点-Target

    Ihh

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    45kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Ihh. AA range:209-258

  • 特异性

    Ihh Polyclonal Antibody detects endogenous levels of Ihh protein.

  • 基因名称

    IHH

  • 蛋白名称

    Indian hedgehog protein

  • 别名

    IHH;Indian hedgehog protein;IHH;HHG-2

  • Organism-1

    Human

  • 基因ID-1

    3549

  • SwissProt-1

    Q14623

  • Organism-2

    Mouse

  • 基因ID-2

    16147

  • SwissProt-2

    P97812

  • 背景

    This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015],

  • 细胞定位

    [Indian hedgehog protein N-product]: Cell membrane ; Lipid-anchor ; Extracellular side . The N-terminal peptide remains associated with the cell surface. .; [Indian hedgehog protein C-product]: Secreted, extracellular space . The C-terminal peptide diffuses from the cell. .; Cell membrane .