FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GABBR2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from GABAB R2 . at AA range: 830-910
特异性
GABAB R2 Polyclonal Antibody detects endogenous levels of GABAB R2 protein.
基因名称
GABBR2
蛋白名称
Gamma-aminobutyric acid type B receptor subunit 2
别名
GABBR2;GPR51;GPRC3B;Gamma-aminobutyric acid type B receptor subunit 2;GABA-B receptor 2;GABA-B-R2;GABA-BR2;GABABR2;Gb2;G-protein coupled receptor 51;HG20
Organism-1
Human
基因ID-1
9568
SwissProt-1
O75899
Organism-2
Mouse
基因ID-2
242425
SwissProt-2
Q80T41
Organism-3
Rat
基因ID-3
83633
SwissProt-3
O88871
背景
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. .
