β-1,4-Gal-T2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616868
- 产品信息
商品描述
靶点-Target
β-1/4-Gal-T2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
42kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human β-1,4-Gal-T2.
特异性
β-1,4-Gal-T2 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T2 protein.
基因名称
B4GALT2
蛋白名称
Beta-1,4-galactosyltransferase 2
别名
B4GALT2;Beta-1;4-galactosyltransferase 2;Beta-1,4-GalTase 2;Beta4Gal-T2;b4Gal-T2;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2
Organism-1
Human
基因ID-1
8704
SwissProt-1
O60909
Organism-2
Mouse
基因ID-2
53418
SwissProt-2
Q9Z2Y2
背景
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity i
细胞定位
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.





