FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ZO-2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
160kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ZO-2. AA range:1063-1112
特异性
ZO-2 Polyclonal Antibody detects endogenous levels of ZO-2 protein.
基因名称
TJP2
蛋白名称
Tight junction protein ZO-2
别名
TJP2;X104;ZO2;Tight junction protein ZO-2;Tight junction protein 2;Zona occludens protein 2;Zonula occludens protein 2
Organism-1
Human
基因ID-1
9414
SwissProt-1
Q9UDY2
Organism-2
Mouse
基因ID-2
21873
SwissProt-2
Q9Z0U1
背景
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Cell junction, adherens junction. Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, tight junction . Nucleus . Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures. .
