ZDHHC2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616801

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商品描述
  • 靶点-Target

    ZDHHC2

  • 反应性

    Human,Mouse,Rat,Monkey

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    42kD

  • 推荐稀释比

    WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range:61-110

  • 特异性

    ZDHHC2 Polyclonal Antibody detects endogenous levels of ZDHHC2 protein.

  • 基因名称

    ZDHHC2

  • 蛋白名称

    Palmitoyltransferase ZDHHC2

  • 别名

    ZDHHC2;REAM;REC;ZNF372;Palmitoyltransferase ZDHHC2;Reduced expression associated with metastasis protein;Ream;Reduced expression in cancer protein;Rec;Zinc finger DHHC domain-containing protein 2;DHHC-2;Zinc finger protein 372

  • Organism-1

    Human

  • 基因ID-1

    51201

  • SwissProt-1

    Q9UIJ5

  • Organism-2

    Mouse

  • 基因ID-2

    70546

  • SwissProt-2

    P59267

  • Organism-3

    Rat

  • SwissProt-3

    Q9JKR5

  • 背景

    catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.,

  • 细胞定位

    Cell junction, synapse, postsynaptic density . Postsynaptic recycling endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Translocates to postsynaptic density when synaptic activity decreases. .