- 产品信息
商品描述
靶点-Target
ZDHHC2
反应性
Human,Mouse,Rat,Monkey
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ZDHHC2. AA range:61-110
特异性
ZDHHC2 Polyclonal Antibody detects endogenous levels of ZDHHC2 protein.
基因名称
ZDHHC2
蛋白名称
Palmitoyltransferase ZDHHC2
别名
ZDHHC2;REAM;REC;ZNF372;Palmitoyltransferase ZDHHC2;Reduced expression associated with metastasis protein;Ream;Reduced expression in cancer protein;Rec;Zinc finger DHHC domain-containing protein 2;DHHC-2;Zinc finger protein 372
Organism-1
Human
基因ID-1
51201
SwissProt-1
Q9UIJ5
Organism-2
Mouse
基因ID-2
70546
SwissProt-2
P59267
Organism-3
Rat
SwissProt-3
Q9JKR5
背景
catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Mutations in ZDHHC2 are found in hepatocellular carcinoma and colorectal cancer.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Ubiquitously expressed. Reduced expression in colorectal cancers.,
细胞定位
Cell junction, synapse, postsynaptic density . Postsynaptic recycling endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Translocates to postsynaptic density when synaptic activity decreases. .





