- 产品信息
商品描述
靶点-Target
ZAC1
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
特异性
ZAC1 Polyclonal Antibody detects endogenous levels of ZAC1 protein.
基因名称
PLAGL1
蛋白名称
Zinc finger protein PLAGL1
别名
PLAGL1;LOT1;ZAC;Zinc finger protein PLAGL1;Lost on transformation 1;LOT-1;Pleiomorphic adenoma-like protein 1;Tumor supressor ZAC
Organism-1
Human
基因ID-1
5325
SwissProt-1
Q9UM63
背景
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],
细胞定位
Nucleus .





