FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
XRCC4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310
特异性
XRCC4 Polyclonal Antibody detects endogenous levels of XRCC4 protein.
基因名称
XRCC4
蛋白名称
DNA repair protein XRCC4
别名
XRCC4;DNA repair protein XRCC4;X-ray repair cross-complementing protein 4
Organism-1
Human
基因ID-1
7518
SwissProt-1
Q13426
Organism-2
Mouse
SwissProt-2
Q924T3
背景
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],
细胞定位
Nucleus . Chromosome . Localizes to site of double-strand breaks. .; [Protein XRCC4, C-terminus]: Cytoplasm . Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3). .
