FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
XRCC1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566
特异性
XRCC1 Polyclonal Antibody detects endogenous levels of XRCC1 protein.
基因名称
XRCC1
蛋白名称
DNA repair protein XRCC1
别名
XRCC1;DNA repair protein XRCC1;X-ray repair cross-complementing protein 1
Organism-1
Human
基因ID-1
7515
SwissProt-1
P18887
Organism-2
Mouse
基因ID-2
22594
SwissProt-2
Q60596
Organism-3
Rat
基因ID-3
84495
SwissProt-3
Q9ESZ0
背景
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
