FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
XPLN
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC:1:50-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGEF3. AA range:456-505
特异性
XPLN Polyclonal Antibody detects endogenous levels of XPLN protein.
基因名称
ARHGEF3
蛋白名称
Rho guanine nucleotide exchange factor 3
别名
ARHGEF3;Rho guanine nucleotide exchange factor 3;Exchange factor found in platelets and leukemic and neuronal tissues;XPLN
Organism-1
Human
基因ID-1
50650
SwissProt-1
Q9NR81
Organism-2
Mouse
基因ID-2
71704
SwissProt-2
Q91X46
背景
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .
