FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
X11β
反应性
Human,Mouse,Rat
应用
IHC,IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
83kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human APBA2. AA range:371-420
特异性
X11β Polyclonal Antibody detects endogenous levels of X11β protein.
基因名称
APBA2
蛋白名称
Amyloid beta A4 precursor protein-binding family A member 2
别名
APBA2;MINT2;X11L;Amyloid beta A4 precursor protein-binding family A member 2;Adapter protein X11beta;Neuron-specific X11L protein;Neuronal Munc18-1-interacting protein 2;Mint-2
Organism-1
Human
基因ID-1
321
SwissProt-1
Q99767
Organism-2
Mouse
基因ID-2
11784
SwissProt-2
P98084
Organism-3
Rat
基因ID-3
83610
SwissProt-3
O35431
背景
amyloid beta precursor protein binding family A member 2(APBA2) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
plasma membrane,synaptic vesicle,
