- 产品信息
商品描述
靶点-Target
WTAP
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human WTAP. AA range:321-370
特异性
WTAP Polyclonal Antibody detects endogenous levels of WTAP protein.
基因名称
WTAP
蛋白名称
Pre-mRNA-splicing regulator WTAP
别名
WTAP;KIAA0105;Pre-mRNA-splicing regulator WTAP;Female-lethal;2;D homolog;hFL;2;D;WT1-associated protein;Wilms tumor 1-associating protein
Organism-1
Human
基因ID-1
9589
SwissProt-1
Q15007
Organism-2
Mouse
基因ID-2
60532
SwissProt-2
Q9ER69
背景
The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in several transcript variants encoding three different isoforms. [provided by RefSeq, Jul 2012],
细胞定位
Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus. .





