FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Wnt-1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human WNT1. AA range:301-350
特异性
Wnt-1 Polyclonal Antibody detects endogenous levels of Wnt-1 protein.
基因名称
WNT1
蛋白名称
Proto-oncogene Wnt-1
别名
WNT1;INT1;Proto-oncogene Wnt-1;Proto-oncogene Int-1 homolog
Organism-1
Human
基因ID-1
7471
SwissProt-1
P04628
Organism-2
Mouse
基因ID-2
22408
SwissProt-2
P04426
背景
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in
细胞定位
Secreted, extracellular space, extracellular matrix . Secreted .
