- 产品信息
商品描述
靶点-Target
WIP
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human WIPF1. AA range:421-470
特异性
WIP Polyclonal Antibody detects endogenous levels of WIP protein.
基因名称
WIPF1
蛋白名称
WAS/WASL-interacting protein family member 1
别名
WIPF1;WASPIP;WIP;WAS/WASL-interacting protein family member 1;Protein PRPL-2;Wiskott-Aldrich syndrome protein-interacting protein;WASP-interacting protein
Organism-1
Human
基因ID-1
7456
SwissProt-1
O43516
Organism-2
Mouse
基因ID-2
215280
SwissProt-2
Q8K1I7
Organism-3
Rat
基因ID-3
117538
SwissProt-3
Q6IN36
背景
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Cell projection, ruffle . Vesicle surfaces and along actin tails. Colocalizes with actin stress fibers. When coexpressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL (By similarity). .





