WIP Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616772

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商品描述
  • 靶点-Target

    WIP

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    52kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human WIPF1. AA range:421-470

  • 特异性

    WIP Polyclonal Antibody detects endogenous levels of WIP protein.

  • 基因名称

    WIPF1

  • 蛋白名称

    WAS/WASL-interacting protein family member 1

  • 别名

    WIPF1;WASPIP;WIP;WAS/WASL-interacting protein family member 1;Protein PRPL-2;Wiskott-Aldrich syndrome protein-interacting protein;WASP-interacting protein

  • Organism-1

    Human

  • 基因ID-1

    7456

  • SwissProt-1

    O43516

  • Organism-2

    Mouse

  • 基因ID-2

    215280

  • SwissProt-2

    Q8K1I7

  • Organism-3

    Rat

  • 基因ID-3

    117538

  • SwissProt-3

    Q6IN36

  • 背景

    This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Cell projection, ruffle . Vesicle surfaces and along actin tails. Colocalizes with actin stress fibers. When coexpressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL (By similarity). .