FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
VEGI
反应性
Human,Rat,Mouse,
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
20kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TNFSF15. AA range:181-230
特异性
VEGI Polyclonal Antibody detects endogenous levels of VEGI protein.
基因名称
TNFSF15
蛋白名称
Tumor necrosis factor ligand superfamily member 15
别名
TNFSF15;TL1;VEGI;Tumor necrosis factor ligand superfamily member 15;TNF ligand-related molecule 1;Vascular endothelial cell growth inhibitor
Organism-1
Human
基因ID-1
9966
SwissProt-1
O95150
Organism-2
Mouse
SwissProt-2
Q5UBV8
背景
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],
细胞定位
Membrane ; Single-pass type II membrane protein .; [Tumor necrosis factor ligand superfamily member 15, secreted form]: Secreted.
