V-ATPase H Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616733
- 产品信息
商品描述
靶点-Target
V-ATPase H
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATP6V1H. AA range:341-390
特异性
V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.
基因名称
ATP6V1H
蛋白名称
V-type proton ATPase subunit H
别名
ATP6V1H;CGI-11;V-type proton ATPase subunit H;V-ATPase subunit H;Nef-binding protein 1;NBP1;Protein VMA13 homolog;V-ATPase 50/57 kDa subunits;Vacuolar proton pump subunit H;Vacuolar proton pump subunit SFD
Organism-1
Human
基因ID-1
51606
SwissProt-1
Q9UI12
Organism-2
Mouse
基因ID-2
108664
SwissProt-2
Q8BVE3
背景
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
细胞定位
Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein .





