V-ATPase H Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616733

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商品描述
  • 靶点-Target

    V-ATPase H

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human ATP6V1H. AA range:341-390

  • 特异性

    V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein.

  • 基因名称

    ATP6V1H

  • 蛋白名称

    V-type proton ATPase subunit H

  • 别名

    ATP6V1H;CGI-11;V-type proton ATPase subunit H;V-ATPase subunit H;Nef-binding protein 1;NBP1;Protein VMA13 homolog;V-ATPase 50/57 kDa subunits;Vacuolar proton pump subunit H;Vacuolar proton pump subunit SFD

  • Organism-1

    Human

  • 基因ID-1

    51606

  • SwissProt-1

    Q9UI12

  • Organism-2

    Mouse

  • 基因ID-2

    108664

  • SwissProt-2

    Q8BVE3

  • 背景

    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

  • 细胞定位

    Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein .