V-ATPase B1 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616730
- 产品信息
商品描述
靶点-Target
V-ATPase B1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATP6V1B1. AA range:381-430
特异性
V-ATPase B1 Polyclonal Antibody detects endogenous levels of V-ATPase B1 protein.
基因名称
ATP6V1B1
蛋白名称
V-type proton ATPase subunit B kidney isoform
别名
ATP6V1B1;ATP6B1;VATB;VPP3;V-type proton ATPase subunit B;kidney isoform;V-ATPase subunit B 1;Endomembrane proton pump 58 kDa subunit;Vacuolar proton pump subunit B 1
Organism-1
Human
基因ID-1
525
SwissProt-1
P15313
背景
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found i
细胞定位
Apical cell membrane . Basolateral cell membrane .





