- 产品信息
商品描述
靶点-Target
USP11
反应性
Human,Mouse,Rat
应用
IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human USP11.
特异性
USP11 Polyclonal Antibody detects endogenous levels of USP11 protein.
基因名称
USP11
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 11
别名
USP11;UHX1;Ubiquitin carboxyl-terminal hydrolase 11;Deubiquitinating enzyme 11;Ubiquitin thioesterase 11;Ubiquitin-specific-processing protease 11
Organism-1
Human
基因ID-1
8237
SwissProt-1
P51784
Organism-2
Mouse
基因ID-2
236733
SwissProt-2
Q99K46
背景
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:12084015, PubMed:15314155). Associates with chromatin (PubMed:20601937, PubMed:20233726). .





