FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
uPA
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
49kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human uPA. AA range:190-239
特异性
uPA Polyclonal Antibody detects endogenous levels of uPA protein.
基因名称
PLAU
蛋白名称
Urokinase-type plasminogen activator
别名
PLAU;Urokinase-type plasminogen activator;U-plasminogen activator;uPA
Organism-1
Human
基因ID-1
5328
SwissProt-1
P00749
Organism-2
Mouse
SwissProt-2
P06869
背景
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],
细胞定位
Secreted .
