UFD2 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616691

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商品描述
  • 靶点-Target

    UFD2

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    146kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the Internal region of human UFD2.

  • 特异性

    UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.

  • 基因名称

    UBE4B

  • 蛋白名称

    Ubiquitin conjugation factor E4 B

  • 别名

    UBE4B;HDNB1;KIAA0684;UFD2;Ubiquitin conjugation factor E4 B;Homozygously deleted in neuroblastoma 1;Ubiquitin fusion degradation protein 2

  • Organism-1

    Human

  • 基因ID-1

    10277

  • SwissProt-1

    O95155

  • Organism-2

    Mouse

  • 基因ID-2

    63958

  • SwissProt-2

    Q9ES00

  • 背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm . Nucleus .