- 产品信息
商品描述
靶点-Target
UFD2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
146kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human UFD2.
特异性
UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.
基因名称
UBE4B
蛋白名称
Ubiquitin conjugation factor E4 B
别名
UBE4B;HDNB1;KIAA0684;UFD2;Ubiquitin conjugation factor E4 B;Homozygously deleted in neuroblastoma 1;Ubiquitin fusion degradation protein 2
Organism-1
Human
基因ID-1
10277
SwissProt-1
O95155
Organism-2
Mouse
基因ID-2
63958
SwissProt-2
Q9ES00
背景
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus .





