UDP-GlcDH Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616689
- 产品信息
商品描述
靶点-Target
UDP-GlcDH
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UGDH. AA range:391-440
特异性
UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.
基因名称
UGDH
蛋白名称
UDP-glucose 6-dehydrogenase
别名
UGDH;UDP-glucose 6-dehydrogenase;UDP-Glc dehydrogenase;UDP-GlcDH;UDPGDH
Organism-1
Human
基因ID-1
7358
SwissProt-1
O60701
Organism-2
Mouse
基因ID-2
22235
SwissProt-2
O70475
Organism-3
Rat
基因ID-3
83472
SwissProt-3
O70199
背景
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
细胞定位
nucleus,nucleoplasm,cytosol,extracellular exosome,





