UDP-GlcDH Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616689

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商品描述
  • 靶点-Target

    UDP-GlcDH

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human UGDH. AA range:391-440

  • 特异性

    UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.

  • 基因名称

    UGDH

  • 蛋白名称

    UDP-glucose 6-dehydrogenase

  • 别名

    UGDH;UDP-glucose 6-dehydrogenase;UDP-Glc dehydrogenase;UDP-GlcDH;UDPGDH

  • Organism-1

    Human

  • 基因ID-1

    7358

  • SwissProt-1

    O60701

  • Organism-2

    Mouse

  • 基因ID-2

    22235

  • SwissProt-2

    O70475

  • Organism-3

    Rat

  • 基因ID-3

    83472

  • SwissProt-3

    O70199

  • 背景

    The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],

  • 细胞定位

    nucleus,nucleoplasm,cytosol,extracellular exosome,