FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UDG
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UNG. AA range:191-240
特异性
UDG Polyclonal Antibody detects endogenous levels of UDG protein.
基因名称
UNG
蛋白名称
Uracil-DNA glycosylase
别名
UNG;DGU;UNG1;UNG15;Uracil-DNA glycosylase;UDG
Organism-1
Human
基因ID-1
7374
SwissProt-1
P13051
Organism-2
Mouse
基因ID-2
22256
SwissProt-2
P97931
背景
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010],
细胞定位
[Isoform 1]: Mitochondrion.; [Isoform 2]: Nucleus.
