FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UCP3
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
33kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UCP3. AA range:259-308
特异性
UCP3 Polyclonal Antibody detects endogenous levels of UCP3 protein.
基因名称
UCP3
蛋白名称
Mitochondrial uncoupling protein 3
别名
UCP3;SLC25A9;Mitochondrial uncoupling protein 3;UCP 3;Solute carrier family 25 member 9
Organism-1
Human
基因ID-1
7352
SwissProt-1
P55916
Organism-2
Mouse
基因ID-2
22229
SwissProt-2
P56501
Organism-3
Rat
基因ID-3
25708
SwissProt-3
P56499
背景
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria.
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
