FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UCP2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
33kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UCP2. AA range:64-113
特异性
UCP2 Polyclonal Antibody detects endogenous levels of UCP2 protein.
基因名称
UCP2
蛋白名称
Mitochondrial uncoupling protein 2
别名
UCP2;SLC25A8;Mitochondrial uncoupling protein 2;UCP 2;Solute carrier family 25 member 8;UCPH
Organism-1
Human
基因ID-1
7351
SwissProt-1
P55851
Organism-2
Mouse
基因ID-2
22228
SwissProt-2
P70406
Organism-3
Rat
基因ID-3
54315
SwissProt-3
P56500
背景
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [prov
细胞定位
Mitochondrion inner membrane; Multi-pass membrane protein.
