- 产品信息
商品描述
靶点-Target
UBR5
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
309kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EDD. AA range:1-50
特异性
UBR5 Polyclonal Antibody detects endogenous levels of UBR5 protein.
基因名称
UBR5
蛋白名称
E3 ubiquitin-protein ligase UBR5
别名
UBR5;EDD;EDD1;HYD;KIAA0896;E3 ubiquitin-protein ligase UBR5;E3 ubiquitin-protein ligase;HECT domain-containing 1;Hyperplastic discs protein homolog;hHYD;Progestin-induced protein
Organism-1
Human
基因ID-1
51366
SwissProt-1
O95071
Organism-2
Mouse
基因ID-2
70790
SwissProt-2
Q80TP3
背景
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.





