UBF-1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616678

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商品描述
  • 靶点-Target

    UBF-1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    90kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human UBF1. AA range:501-550

  • 特异性

    UBF-1 Polyclonal Antibody detects endogenous levels of UBF-1 protein.

  • 基因名称

    UBTF

  • 蛋白名称

    Nucleolar transcription factor 1

  • 别名

    UBTF;UBF;UBF1;Nucleolar transcription factor 1;Autoantigen NOR-90;Upstream-binding factor 1;UBF-1

  • Organism-1

    Human

  • 基因ID-1

    7343

  • SwissProt-1

    P17480

  • Organism-2

    Mouse

  • SwissProt-2

    P25976

  • Organism-3

    Rat

  • 基因ID-3

    25574

  • SwissProt-3

    P25977

  • 背景

    This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011],

  • 细胞定位

    Nucleus, nucleolus .