FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UBE2D2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
17kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human UBE2D2. AA range:98-147
特异性
UBE2D2 Polyclonal Antibody detects endogenous levels of UBE2D2 protein.
基因名称
UBE2D2
蛋白名称
Ubiquitin-conjugating enzyme E2 D2
别名
UBE2D2;UBC4;UBC5B;UBCH4;UBCH5B;Ubiquitin-conjugating enzyme E2 D2;Ubiquitin carrier protein D2;Ubiquitin-conjugating enzyme E2;17;KB 2;Ubiquitin-conjugating enzyme E2-17 kDa 2;Ubiquitin-protein ligase D2
Organism-1
Human
基因ID-1
7322
SwissProt-1
P62837
Organism-2
Mouse
基因ID-2
56550
SwissProt-2
P62838
Organism-3
Rat
基因ID-3
641452
SwissProt-3
P62839
背景
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013],
细胞定位
ubiquitin ligase complex,nucleoplasm,cytosol,protein complex,extracellular exosome,
