T-type Ca++ CP α1H Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616647
- 产品信息
商品描述
靶点-Target
T-type Ca++ CP α1H
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
259kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CACNA1H. AA range:462-511
特异性
T-type Ca++ CP α1H Polyclonal Antibody detects endogenous levels of T-type Ca++ CP α1H protein.
基因名称
CACNA1H
蛋白名称
Voltage-dependent T-type calcium channel subunit alpha-1H
别名
CACNA1H;Voltage-dependent T-type calcium channel subunit alpha-1H;Low-voltage-activated calcium channel alpha1 3.2 subunit;Voltage-gated calcium channel subunit alpha Cav3.2
Organism-1
Human
基因ID-1
8912
SwissProt-1
O95180
Organism-2
Mouse
SwissProt-2
O88427
Organism-3
Rat
基因ID-3
114862
SwissProt-3
Q9EQ60
背景
calcium voltage-gated channel subunit alpha1 H(CACNA1H) Homo sapiens This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein . Interaction with STAC increases expression at the cell membrane. .





