FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TTF-1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TTF-1. AA range:27-76
特异性
TTF-1 Polyclonal Antibody detects endogenous levels of TTF-1 protein.
基因名称
NKX2-1
蛋白名称
Homeobox protein Nkx-2.1
别名
NKX2-1;NKX2A;TITF1;TTF1;Homeobox protein Nkx-2.1;Homeobox protein NK-2 homolog A;Thyroid nuclear factor 1;Thyroid transcription factor 1;TTF-1
Organism-1
Human
基因ID-1
7080
SwissProt-1
P43699
Organism-2
Mouse
基因ID-2
21869
SwissProt-2
P50220
Organism-3
Rat
SwissProt-3
P23441
背景
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],
细胞定位
Nucleus .
