FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TRβ1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
53kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta. AA range:11-60
特异性
TRβ1 Polyclonal Antibody detects endogenous levels of TRβ1 protein.
基因名称
THRB
蛋白名称
Thyroid hormone receptor beta
别名
THRB;ERBA2;NR1A2;THR1;Thyroid hormone receptor beta;Nuclear receptor subfamily 1 group A member 2;c-erbA-2;c-erbA-beta
Organism-1
Human
基因ID-1
7068
SwissProt-1
P10828
Organism-2
Mouse
基因ID-2
21834
SwissProt-2
P37242
Organism-3
Rat
SwissProt-3
P18113
背景
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.
