FGF-2 Polyclonal Antibody
¥680.00
Tropomyosin α Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2616620
- 产品信息
商品描述
靶点-Target
Tropomyosin α
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Tropomyosin alpha. AA range:40-89
特异性
Tropomyosin α Polyclonal Antibody detects endogenous levels of Tropomyosin α protein.
基因名称
TPM1
蛋白名称
Tropomyosin alpha-1 chain
别名
TPM1;C15orf13;TMSA;Tropomyosin alpha-1 chain;Alpha-tropomyosin;Tropomyosin-1
Organism-1
Human
基因ID-1
7168
SwissProt-1
P09493
Organism-2
Mouse
基因ID-2
22003
SwissProt-2
P58771
Organism-3
Rat
基因ID-3
24851
SwissProt-3
P04692
背景
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by
细胞定位
Cytoplasm, cytoskeleton . Associates with F-actin stress fibers. .
