- 产品信息
商品描述
靶点-Target
Treacle
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
152kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TCOF1. AA range:41-90
特异性
Treacle Polyclonal Antibody detects endogenous levels of Treacle protein.
基因名称
TCOF1
蛋白名称
Treacle protein
别名
TCOF1;Treacle protein;Treacher Collins syndrome protein
Organism-1
Human
基因ID-1
6949
SwissProt-1
Q13428
Organism-2
Mouse
基因ID-2
21453
SwissProt-2
O08784
背景
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
细胞定位
Nucleus, nucleolus .





