- 产品信息
商品描述
靶点-Target
TRAP240
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
239kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MED13. AA range:681-730
特异性
TRAP240 Polyclonal Antibody detects endogenous levels of TRAP240 protein.
基因名称
MED13
蛋白名称
Mediator of RNA polymerase II transcription subunit 13
别名
MED13;ARC250;KIAA0593;THRAP1;TRAP240;Mediator of RNA polymerase II transcription subunit 13;Activator-recruited cofactor 250 kDa component;ARC250;Mediator complex subunit 13;Thyroid hormone receptor-associated protein 1;Thyroid ho
Organism-1
Human
基因ID-1
9969
SwissProt-1
Q9UHV7
Organism-2
Mouse
SwissProt-2
Q5SWW4
背景
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.





