FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
TRADD
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300
特异性
TRADD Polyclonal Antibody detects endogenous levels of TRADD protein.
基因名称
TRADD
蛋白名称
Tumor necrosis factor receptor type 1-associated DEATH domain protein
别名
TRADD;Tumor necrosis factor receptor type 1-associated DEATH domain protein;TNFR1-associated DEATH domain protein;TNFRSF1A-associated via death domain
Organism-1
Human
基因ID-1
8717
SwissProt-1
Q15628
Organism-2
Mouse
基因ID-2
71609
SwissProt-2
Q3U0V2
背景
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. .
