- 产品信息
商品描述
靶点-Target
TRAC-1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RNF125. AA range:131-180
特异性
TRAC-1 Polyclonal Antibody detects endogenous levels of TRAC-1 protein.
基因名称
RNF125
蛋白名称
E3 ubiquitin-protein ligase RNF125
别名
RNF125;E3 ubiquitin-protein ligase RNF125;RING finger protein 125;T-cell RING activation protein 1;TRAC-1
Organism-1
Human
基因ID-1
54941
SwissProt-1
Q96EQ8
Organism-2
Mouse
基因ID-2
67664
SwissProt-2
Q9D9R0
背景
ring finger protein 125(RNF125) Homo sapiens This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012],
细胞定位
Golgi apparatus membrane ; Lipid-anchor . Shows a reticular staining pattern within the cell and is probably expressed at other intracellular membranes in addition to the Golgi membrane. Not detected at the plasma membrane. .





